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Structural conformation of a protein is one of the most important factors to measure its functional similarity and molecular evolutionary relationship with the other proteins. To discover the functional relationship among rapidly increasing numbers of protein structures, an efficient and effective tool for multiple structure alignment (MStA) has become extremely important.

AIR can be considered as an extra auxiliary module and combined with all other structural alignment tools for improving their originally aligned results, and AIR itself can achieve multiple structure alignment independently and provide an outstanding performance compared to those famous systems.

AIR has shown its strength on not only a better aligned result, but also a shorter computational time, especially for the cases of multiple structure alignment. We hope AIR can help you to obtain the best aligned results for your query protein structures.